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Premier Control Technologies Fluid Solutions

Life Sciences

Life Sciences — Flow, Pressure, Dosing & Gas Handling (UK & Ireland)

Introduction

The Life Sciences group spans R&D to GMP adjacent production across pharmaceutical, biochemistry, biotechnology, medical, hospitals, and fisheries. These environments demand hygienic design, repeatable gas/liquid control, documented materials (316L/USP Class VI where applicable), and easy data connectivity to PLC/SCADA/LIMS.

Our higher level Life Sciences page ties together the common challenges—sterility, validation, low shear transfer, precise gas handling.


Life Sciences sub markets we serve:

  • Pharmaceutical — sterile utilities, hydrogenation/test gases, aseptic dosing & filling.
  • Biochemistry — scCO₂ processing, chromatography back pressure, UF/DF, sterile transfer.
  • Biotechnology — bioreactor gas control, media/buffer prep, single use skids.
  • Medical — device testing, diagnostics OEMs, leak/flow simulation under controlled atmospheres.
  • Hospitals — medical gas & AGSS control/monitoring, estates utilities & water loops.
  • Fisheries — life support utilities and process control within the broader Life Sciences group.

Product groups that serve Life Sciences

Fluid Metering (FMI) — Valveless piston metering & micro dosing

Where it fits: aseptic filling, assay/reagent make up, micro ingredient addition (pharma, biotech, biochemistry, medical).

Why it’s used: one moving part (valveless ceramic internals) delivers ultra repeatable micro to mL scale doses with low maintenance and excellent chemical compatibility.

Key products:

Benefits to Life Sciences:

  • Precision & repeatability for critical fills and analytical prep; ceramic wetted path resists wear and many solvents.
  • Low maintenance, valveless architecture reduces downtime and validation effort.

Richards Industrials — Steriflow, Jordan Valve & LowFlow

Where it fits: sterile utilities (clean steam, WFI/PUW, clean gases), buffer/media control, pilot skids and fractional flow control.

Brands & representative products:

  • Steriflow (sanitary/hygienic)
  • Jordan Valve (utilities & pilot)
  • LowFlow (fractional flow control)
    • 708 / 708HP & JR/JRH low Cv control and high pressure regulation for sampler skids, lab rigs and specialty gases when ultra fine resolution is needed.

Benefits to Life Sciences:

  • Hygienic compliance & documentation (Steriflow) for validated pharma/biotech services.
  • Tight, repeatable control across both sanitary and non sanitary utilities with compact options for skids and benches (Jordan Valve, LowFlow).
  • Single supplier family simplifies specification across sterile utilities, pilot plants and fractional flow applications.

Mass flow & electronic pressure control

Alicat Scientific

  • BIO Series Mass Flow Controllers — designed for bioprocessing: 10,000:1 range, 316L/USP Class VI elastomers, moisture tolerant build, optional IP66, and broad industrial protocols for PAT/Pharma 4.0 integration. Ideal for bioreactor O₂/CO₂/N₂/air control and sparging.
  • Pressure Controllers (PC/PCD/PC3/PCR) — fast closed loop pressure, gauge/absolute/differential; single and dual valve options for line, back pressure and closed volume control in tests and process skids.

Back pressure & vacuum regulation

Equilibar

  • Research/General/Industrial Series BPRs — dome loaded, multi orifice diaphragm technology that holds ultra stable upstream pressure at very low to high flows, including mixed phase media; excellent for chromatography outlet control, membrane processes, reactors and CO₂ compression legs.
  • EVR Precision Vacuum Regulators — frictionless vacuum control from benchtop to pilot scale—useful for lab reactors, vacuum filtration and sampling.
  • SD Biopharmaceutical (single use) BPRs — USP Class VI polymer flow path with 316 SS support; sterilizable and disposable for UF/DF, TFF and other single use bioprocess skids.

Sanitary regulators & control valves

Steriflow (Richards Industrials)

Peristaltic & valveless piston pumps

  • Longer L600 1F / WT600 1F — programmable peristaltic drives (recipe steps, copy counts, back suction) with analog/RS 485 for PLCs; ideal for media/buffer prep, sanitant dosing and sterile transfer.
  • FMI (Fluid Metering) FENYX® / TRYTON™ — valveless ceramic internals metering for ultra precise micro to mL scale dosing in final fill, assay reagents and fragrance/actives; low maintenance, drift resistant.

UHP & high purity gas regulation

Non intrusive liquid flow measurement

  • Dynasonics TFX 5000 clamp on ultrasonic — permanent, no breach metering for WFI/PUW, chilled/thermal loops and process water, with Modbus/BACnet/EtherNet IP and onboard logging/energy options.

Gas mixing & controlled atmospheres

  • Fusion Flow MXM/IMX — precise, programmable multi gas blending (up to 10 channels; ±0.6% mix accuracy; ~25 ms response) for incubators, gloveboxes, simulation labs and method development.

Typical applications we solve (how & why)

Pharmaceutical

  • Clean steam & utilities pressure controlSteriflow Mark 96 sanitary regulators maintain validated SIP/CIP cycles; documented materials and finishes support audits.
  • Aseptic filling & micro dosingFMI FENYX®/TRYTON™ deliver accurate, low pulsation dosing with minimal wear parts for final fill and assay prep.

Biochemistry

  • Chromatography outlet back pressureEquilibar Research Series eliminates stiction/hysteresis for consistent retention/peak shape at very low flows.
  • WFI/PUW verification without breachDynasonics TFX 5000 clamps on, enabling continuous metering and energy audits with no downtime.

Biotechnology

  • Bioreactor gas control (O₂/CO₂/N₂/air)Alicat BIO provides 10,000:1 control with 316L/USP Class VI elastomers and moisture tolerant construction—ideal for upstream gas trains.
  • Single use UF/DF back pressureEquilibar SD single use BPRs hold tight TMP while simplifying changeover/validation.

Medical

  • Device & diagnostics testing — Alicat pressure/flow platforms (EPC/MFCs) enable rapid set point steps and multi gas libraries for benchtop rigs; broad protocol support speeds OEM integration.

Hospitals

  • Estates water & energy monitoringDynasonics TFX 5000 provides non intrusive monitoring of chilled/domestic loops; industrial comms feed BMS for alarms and trending.
  • Lab calibration gas supplyDrastar two stage UHP maintains stable outlet and purity to GC/analytical instruments.

Fisheries

  • Incubator/holding atmospheresFusion Flow MXM blends
  • — O₂/air/CO₂/N₂ precisely to support life support and R&D environments within this Life Sciences segment.