Life Sciences — Flow, Pressure, Dosing & Gas Handling (UK & Ireland)
Introduction
The Life Sciences group spans R&D to GMP adjacent production across pharmaceutical, biochemistry, biotechnology, medical, hospitals, and fisheries. These environments demand hygienic design, repeatable gas/liquid control, documented materials (316L/USP Class VI where applicable), and easy data connectivity to PLC/SCADA/LIMS.
Our higher level Life Sciences page ties together the common challenges—sterility, validation, low shear transfer, precise gas handling.
Life Sciences sub markets we serve:
- Pharmaceutical — sterile utilities, hydrogenation/test gases, aseptic dosing & filling.
- Biochemistry — scCO₂ processing, chromatography back pressure, UF/DF, sterile transfer.
- Biotechnology — bioreactor gas control, media/buffer prep, single use skids.
- Medical — device testing, diagnostics OEMs, leak/flow simulation under controlled atmospheres.
- Hospitals — medical gas & AGSS control/monitoring, estates utilities & water loops.
- Fisheries — life support utilities and process control within the broader Life Sciences group.
Product groups that serve Life Sciences
Fluid Metering (FMI) — Valveless piston metering & micro dosing
Where it fits: aseptic filling, assay/reagent make up, micro ingredient addition (pharma, biotech, biochemistry, medical).
Why it’s used: one moving part (valveless ceramic internals) delivers ultra repeatable micro to mL scale doses with low maintenance and excellent chemical compatibility.
Key products:
Benefits to Life Sciences:
- Precision & repeatability for critical fills and analytical prep; ceramic wetted path resists wear and many solvents.
- Low maintenance, valveless architecture reduces downtime and validation effort.
Richards Industrials — Steriflow, Jordan Valve & LowFlow
Where it fits: sterile utilities (clean steam, WFI/PUW, clean gases), buffer/media control, pilot skids and fractional flow control.
Brands & representative products:
- Steriflow (sanitary/hygienic)
- Jordan Valve (utilities & pilot)
- LowFlow (fractional flow control)
- 708 / 708HP & JR/JRH low Cv control and high pressure regulation for sampler skids, lab rigs and specialty gases when ultra fine resolution is needed.
Benefits to Life Sciences:
- Hygienic compliance & documentation (Steriflow) for validated pharma/biotech services.
- Tight, repeatable control across both sanitary and non sanitary utilities with compact options for skids and benches (Jordan Valve, LowFlow).
- Single supplier family simplifies specification across sterile utilities, pilot plants and fractional flow applications.
Mass flow & electronic pressure control
Alicat Scientific
- BIO Series Mass Flow Controllers — designed for bioprocessing: 10,000:1 range, 316L/USP Class VI elastomers, moisture tolerant build, optional IP66, and broad industrial protocols for PAT/Pharma 4.0 integration. Ideal for bioreactor O₂/CO₂/N₂/air control and sparging.
- Pressure Controllers (PC/PCD/PC3/PCR) — fast closed loop pressure, gauge/absolute/differential; single and dual valve options for line, back pressure and closed volume control in tests and process skids.
Back pressure & vacuum regulation
Equilibar
- Research/General/Industrial Series BPRs — dome loaded, multi orifice diaphragm technology that holds ultra stable upstream pressure at very low to high flows, including mixed phase media; excellent for chromatography outlet control, membrane processes, reactors and CO₂ compression legs.
- EVR Precision Vacuum Regulators — frictionless vacuum control from benchtop to pilot scale—useful for lab reactors, vacuum filtration and sampling.
- SD Biopharmaceutical (single use) BPRs — USP Class VI polymer flow path with 316 SS support; sterilizable and disposable for UF/DF, TFF and other single use bioprocess skids.
Sanitary regulators & control valves
Steriflow (Richards Industrials)
Peristaltic & valveless piston pumps
- Longer L600 1F / WT600 1F — programmable peristaltic drives (recipe steps, copy counts, back suction) with analog/RS 485 for PLCs; ideal for media/buffer prep, sanitant dosing and sterile transfer.
- FMI (Fluid Metering) FENYX® / TRYTON™ — valveless ceramic internals metering for ultra precise micro to mL scale dosing in final fill, assay reagents and fragrance/actives; low maintenance, drift resistant.
UHP & high purity gas regulation
Non intrusive liquid flow measurement
- Dynasonics TFX 5000 clamp on ultrasonic — permanent, no breach metering for WFI/PUW, chilled/thermal loops and process water, with Modbus/BACnet/EtherNet IP and onboard logging/energy options.
Gas mixing & controlled atmospheres
- Fusion Flow MXM/IMX — precise, programmable multi gas blending (up to 10 channels; ±0.6% mix accuracy; ~25 ms response) for incubators, gloveboxes, simulation labs and method development.
Typical applications we solve (how & why)
Pharmaceutical
- Clean steam & utilities pressure control — Steriflow Mark 96 sanitary regulators maintain validated SIP/CIP cycles; documented materials and finishes support audits.
- Aseptic filling & micro dosing — FMI FENYX®/TRYTON™ deliver accurate, low pulsation dosing with minimal wear parts for final fill and assay prep.
Biochemistry
- Chromatography outlet back pressure — Equilibar Research Series eliminates stiction/hysteresis for consistent retention/peak shape at very low flows.
- WFI/PUW verification without breach — Dynasonics TFX 5000 clamps on, enabling continuous metering and energy audits with no downtime.
Biotechnology
- Bioreactor gas control (O₂/CO₂/N₂/air) — Alicat BIO provides 10,000:1 control with 316L/USP Class VI elastomers and moisture tolerant construction—ideal for upstream gas trains.
- Single use UF/DF back pressure — Equilibar SD single use BPRs hold tight TMP while simplifying changeover/validation.
Medical
- Device & diagnostics testing — Alicat pressure/flow platforms (EPC/MFCs) enable rapid set point steps and multi gas libraries for benchtop rigs; broad protocol support speeds OEM integration.
Hospitals
- Estates water & energy monitoring — Dynasonics TFX 5000 provides non intrusive monitoring of chilled/domestic loops; industrial comms feed BMS for alarms and trending.
- Lab calibration gas supply — Drastar two stage UHP maintains stable outlet and purity to GC/analytical instruments.
Fisheries
- Incubator/holding atmospheres — Fusion Flow MXM blends
— O₂/air/CO₂/N₂ precisely to support life support and R&D environments within this Life Sciences segment.