Premier Control Technologies Fluid Solutions
Pharmaceutical manufacturing demands precision, sterility, and compliance at every stage—from active ingredient synthesis to final product testing. Processes such as hydrogenation, inhalation simulation, bioreactor gas control, and aseptic filling require accurate flow, pressure, and environmental control to ensure product quality and regulatory adherence.
At Premier Control Technologies, we provide validated solutions for gas and liquid handling, clean steam systems, and critical utilities. Our portfolio includes mass flow controllers, sanitary valves, peristaltic pumps, and advanced instrumentation, all designed to meet GMP, ASME BPE, and USP Class VI standards.
Hydrogenation is a critical step in API synthesis, requiring precise hydrogen flow and pressure control to ensure safety and consistent yield. Variations in gas delivery can compromise reaction efficiency and product purity. Maintaining stable conditions is essential for compliance with GMP and safety standards.
Respiratory drug delivery testing requires accurate simulation of breathing patterns to validate inhalers and nebulisers. These tests replicate real-world conditions, including variable humidity and flow rates, to ensure therapeutic effectiveness.
Biologics production relies on controlled O₂, CO₂, and N₂ delivery for cell culture growth. Maintaining precise gas ratios ensures optimal cell viability and productivity, while reducing contamination risk.
Sterile filling of vials, syringes, and cartridges demands high accuracy and contamination control. Any deviation can lead to costly product loss and regulatory issues.
CIP/SIP, WFI, and clean steam loops require hygienic valves to maintain sterility and prevent contamination. These systems are critical for cleaning and sterilisation in pharmaceutical plants.
Tablet coating and drying processes require controlled airflow and humidity to ensure uniform coating and prevent degradation. Poor control can lead to uneven coating and compromised product stability.
Filtration systems and CIP/SIP cycles demand precise pressure and flow control to maintain sterility and cleaning efficiency. Incorrect pressure can damage filters or compromise cleaning.
Pharmaceutical facilities must monitor cleanroom conditions, compressed air quality, and utility gases to comply with GMP. Continuous monitoring ensures product safety and regulatory compliance.
Freeze drying is critical for stabilising sensitive drug products. It requires precise vacuum and temperature control to ensure product integrity.
Packaging integrity is essential to maintain sterility and shelf life. Leak testing ensures container closure integrity for vials, syringes, and blister packs.
| Application | Recommended Technologies | Why It Helps |
|---|---|---|
| Hydrogenation | Alicat MFCs & Pressure Controllers | Accurate H₂ flow & pressure control |
| Inhalation/Exhalation | Dual-Valve Flow Controllers | Bi-directional flow & humidity simulation |
| Bioreactor Gas Control | Alicat BIO Series, CODA Coriolis | Wide turndown, CIP/SIP, Pharma 4.0 ready |
| Aseptic Filling | Peristaltic Pumps, Micro-gear Pumps | Single-use, GMP compliance, low pulsation |
| Clean Steam & Utilities | Steriflow Regulators & Control Valves | ASME BPE, FDA/USP VI, self-draining designs |
| Tablet Coating & Drying | Humidity Sensors, MFCs | Stable airflow & humidity control |
| Sterile Filtration | Steriflow Regulators, Alicat PCs | Accurate pressure for filter integrity |
| Environmental Monitoring | Humidity, Temperature, Pressure Sensors | Continuous GMP compliance |
| Lyophilisation | Pressure Transmitters, MFCs | Accurate vacuum & backfill control |
| Packaging & Leak Testing | MFCs & Pressure Controllers | Reliable leak detection & compliance |
FENYX Variable Dispense Pump
STF Micro Volume Adjustable Dispensing Pump
STFQ Micro Volume Adjustable Displacement Dispenser Pump
Metering Pump
FDD Pulseless Nanoliter Pump
Duplex Precision Mixing Pump
FMI RHV Series Low Flow Variable Speed Pump
FMI RHB Series Direct Current Pump 
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